Intensive WrinkleSpot Treatment A+ is a highly effective targeted treatment for mature skin prone to wrinkles, age spots and loss of firmness. With Pure Retinol Advanced technology, it works intensively against visible signs of aging and clinical studies confirm visible results after just 7 days, with further improvement after up to 8 weeks of regular use. As part of the Vital Perfection range, it combines advanced science with luxurious care to help skin appear firmer, tighter and more radiant.